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A route to a wide range of cyclopentanecarboxylic acids via 4-substituted camphors

โœ Scribed by Volodymyr O. Knizhnikov; Zoya V. Voitenko; Vladimir B. Golovko; Marian V. Gorichko


Book ID
113929220
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
691 KB
Volume
68
Category
Article
ISSN
0040-4020

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## Abstract A new synthetic route to 4โ€substitutedโ€2,2โ€ฒโ€bithiophenes has been developed utilizing 4โ€bromoโ€2,2โ€ฒโ€bithiophene (1). Formation of the bithienyllithium adduct __via__ halogenโ€metal exchange was found to be problematic and resulted in complex mixtures of products. The Grignard reagent of 1