A role for the urokinase-type plasminogen activator system in amyotrophic lateral sclerosis
β Scribed by M. Glas; B. Popp; B. Angele; U. Koedel; C. Chahli; W.A. Schmalix; J.M. Anneser; H.W. Pfister; S. Lorenzl
- Book ID
- 116459186
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 1001 KB
- Volume
- 207
- Category
- Article
- ISSN
- 0014-4886
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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst
The cDNA probe puPAR-2 detects two PstI polymorphisms in the urokinase-type plasminogen activator receptor gene (PLAUR). This probe and the polymorphic system are described.