A role for MAP kinase in the antitumor activity of a nucleoside analog
β Scribed by Whartenby, Katharine A; Darnowski, James W; Freeman, Scott M; Calabresi, Paul
- Book ID
- 110018849
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 430 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0929-1903
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π SIMILAR VOLUMES
## Abstract It has been observed through the conformational analysis of nucleoside analogues that in most of the cases these molecules possess similar conformations to their parent molecules. Therefore, it is, generally believed that these molecules are incorporated as such in the nucleic acids dur
## Abstract Clofarabine is a newβgeneration nucleoside analog that has been synthesized to combine the most favorable pharmacokinetic properties of its congeners fludarabine and cladribine. In addition to inhibition of DNA polymerases and DNA synthesis, clofarabine acts as a strong inhibitor of rib