Role of EGF receptor transactivation in
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Bukhtiar H. Shah; Adrienne Neithardt; David B. Chu; Farzana B. Shah; Kevin J. Ca
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Article
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2005
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John Wiley and Sons
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English
β 679 KB
## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGFβR), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3βkinase (PI3K) is one of the important cell su