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A role for E2F1 in Ras activation of p21(WAF1/CIP1) transcription

✍ Scribed by Gartel, Andrei L; Najmabadi, Feridoon; Goufman, Eugene; Tyner, Angela L

Book ID
110062757
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
207 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Butyric acid is well recognized as a histone deacetylase (HDAC) inhibitor, and changes in histone acetylation are thought to alter gene expression. The mechanism by which sodium butyrate (NaB) induces p21^WAF1/CIP1^, a critical gene involved in the antiproliferative effect of NaB, was s