𝔖 Bobbio Scriptorium
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A road to kidney tubules via the Wnt pathway

✍ Scribed by S. J. Vainio; M. S. Uusitalo


Book ID
106162191
Publisher
Springer
Year
2000
Tongue
English
Weight
223 KB
Volume
15
Category
Article
ISSN
0931-041X

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Members of the Wnt family of secreted glycoproteins act as short-range signaling molecules in vertebrate embryogenesis. Previous work has shown that Wnt-4 is required for kidney development. Mice lacking functional Wnt-4 fail to form pretubular cell aggregates. Wnt-4 acts as an autoinducer of the me