A-ring iodination of estradiol
โ Scribed by Sweet, Frederick; Patrick, Timothy B.; Mudd, Jackquline M.
- Book ID
- 127003293
- Publisher
- American Chemical Society
- Year
- 1979
- Tongue
- English
- Weight
- 460 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
exchange labeling Estradiol and its mono and diiodo derivatives were converted to their 17-diphosphate analogs. Radioiodine labeling of monoiodinated eetradiol diphosphates with 1251 proceeds smoothly in cuprous chloride catalyzed exchange reaction utilizing acetonitrile-ethanol (1:l) as a solvent.
Reaction involving iodine and cupric chloride has been applied to the synthesis of iodinated dihydrotestosterones while radiolabelled estradiol-17-diphosphates and dihydrotestosterone were prepared by the same path using Na .