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A regiochemical study of the alkylation of 1,5- and 2,5-substituted tetrazoles

โœ Scribed by Thomas, Edward W.; Cudahy, Michele M.


Book ID
121368587
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
625 KB
Volume
58
Category
Article
ISSN
0022-3263

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Novel regioselective N-alkylations of 5-
โœ Marija Prhavc; Jozห‡e Kobe ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 178 KB

Regioselective alkylation of 5-substituted-2H-tetrazoles 1 to 2-alkyl derivatives 3 was achieved via decarboxylative alkylation with alkyl cyanoformates. Lesser selectivity was observed with chloroformates.