𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A rapid gas-chromatographic method for the determination of drugs in clinical toxicology

✍ Scribed by R. Pentz; A. Schütt

Publisher
Springer-Verlag
Year
1978
Tongue
English
Weight
520 KB
Volume
39
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.

✦ Synopsis

A rapid gas-chromatographic method for the qualitative and quantitative measurement of various drugs in human plasma and other body fluids has been developed. The extraction procedure is done within 5 min, and gas-chromatographic measurement carried out on 2 diverse columns with detection by flame ionisation detectors. The detection sensitivity of most drugs is high enough to determine their plasma levels in suicidally or accidentally poisoned patients. As shown for 6 different drugs, the limit of detection, the reproducibility and the accuracy are sufficient even for analysis of therapeutical plasma concentrations.

📜 SIMILAR VOLUMES

A rapid gas chromatographic method for t
A rapid gas chromatographic method for the determination of diazepam and metabolites in body fluids
✍ A.G. Howard; G. Nickless; D.M. Hailey 📂 Article 📅 1974 🏛 Elsevier Science 🌐 English ⚖ 341 KB

A rapid method is described for the extraction of diazepam and its metabolites from plasma and urine. The procedure is applicable to subsequent analysis by electron capture gas chromatography, and has been used for the analysis of clinical samples. The detection limit for diazepam is about 0.01 (ug/

A rapid gas-liquid chromatographic metho
A rapid gas-liquid chromatographic method for determining oxalic acid in biological materials
✍ John M.L. Mee; Richard W. Stanley 📂 Article 📅 1973 🏛 Elsevier Science 🌐 English ⚖ 181 KB

A rapid gas-liquid chromatographic method far determining oxalic acid in biological materials' A number of gas cllromntographic (GC) methods for the analysis of the methyl ester of osalic acid in l~iological mntcrinls have hen reportedl-4. However, clifliculties in sample treatments : cg., isolatio

A rapid gas chromatographic method for t
A rapid gas chromatographic method for the determination of poly-β-hydroxybutyric acid in microbial biomass
✍ G. Braunegg; B. Sonnleitner; R. M. Lafferty 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 446 KB

The gas chromatographic method for the determination of poly-/3-hydroxybutyric acid (PHB) consists of a mild acid or alkaline methanolysis of poly-~-hydroxybutyric acid directly without previous extraction of PHB from the cells; this is followed by gas chromatography of the 3-hydroxybutyric acid met