Perhydrofuro-2,3b furans have been prepared in high yield by radical cyclisation of unsaturated bromo acetals. Their transformation into tetrahydro derivatives is described along with a radical annelation to 2,3-dihydrofurans by tributyltin iodoacetate.
A radical cyclisation reaction based strategy to 2,3,5-tri- and tetrasubstituted furans
β Scribed by A. Srikrishna; G. Sundarababu
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 558 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0040-4020
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bromofuran, reactions that require an electrophilic
Regioselective Pd(0)-Catalyzed Coupling Reactions on Methyl 2,3-Dibromofuran-5-carboxylate as a Facile Entry into 2,3,5-Tri-and 2,3-Disubstituted Furans. -The 2,3-dibrominated furan (I) undergoes efficient Pd-catalyzed cross-coupling reactions with a variety of organometallic reagents to yield prod