A preliminary study on the possible role for luetinizing hormone in androgen independent growth of prostate
โ Scribed by V Sriraman; Veena S Rao; N Rajesh; S.S. Vasan; AJ Rao
- Book ID
- 119611249
- Publisher
- Reproductive Healthcare Ltd
- Year
- 2001
- Tongue
- English
- Weight
- 458 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1472-6491
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๐ SIMILAR VOLUMES
## Abstract Androgen receptor (AR) mutations that modify both the ligand binding and the transactivation capacities of the AR represent one of the mechanisms involved in the transition of prostate cancer (PCa) from androgenโdependent to androgenโindependent growth. We use a yeastโbased functional a
Experiments have been performed to clarify whether LHRH agonists might decrease growth of hormone-unresponsive prostate cancer in vivo. Male nude mice were injected s.c. with the human androgen-independent prostate tumor DU 145 cells; osmotic minipumps releasing the LHRH agonist Zoladex (LHRH-A) for