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A possible role for epidermal growth factor and its receptor in the growth of human prostatic and renal cell carcinoma cell lines in athymic nude mice

✍ Scribed by Zhao, X.; van Steenbrugge, G.J.; Foekens, J.A.; Schröder, F.H.

Book ID
123238550
Publisher
Elsevier Science
Year
1990
Weight
178 KB
Volume
26
Category
Article
ISSN
0277-5379

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We examined 22 cases of renal-cell carcinoma (RCC) for structural alterations of the epidermal growth factor receptor (ECFR) gene and found gene amplification in one case of high-stag+high-grade RCC. Dot blot analysis of the total RNA from tumorous and normal kidney tissues revealed overexpression o