A predictive method for the solubility of drug in supercritical carbon dioxide
โ Scribed by Wang, Li-Hsin; Lin, Shiang-Tai
- Book ID
- 121727415
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 983 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0896-8446
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๐ SIMILAR VOLUMES
A new experimental method has been developed for measuring the equilibrium solubility of heavy solutes in supercritical CO2. The micro-SFE (supercritical-fluid extraction) is coupled to supercriticalfluid chromatography (SFC), both operating under the same temperature, pressure, and CO2 flowrate. Na
Predictions are given for the solubilities of four compounds (naphthalene, phenanthrene, phenol, and 2-naphthol) in carbon dioxide at six temperatures between 40 "C and 100 "C and pressures up to 240 bar. The data are intended to be relevant to the extraction of coal-gasification tars. The Peng-Robi