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A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

✍ Scribed by Sucunza, David; Samadi, Abdelouahid; Chioua, Mourad; Silva, Daniel B.; Yunta, Cristina; Infantes, Lourdes; Carmo Carreiras, M.; Soriano, Elena; Marco-Contelles, José


Book ID
120409000
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
674 KB
Volume
47
Category
Article
ISSN
1359-7345

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Solid-phase synthesis of imidazo[1,2-a]p
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; Gérald Guillaume 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.