A Practical Synthesis of L-FMAU from L-Arabinose
โ Scribed by Du, Jinfa; Choi, Yongseok; Lee, Kyeong; Chun, Byoung K.; Hong, Joon H.; Chu, Chung. K.
- Book ID
- 120745376
- Publisher
- Taylor and Francis Group
- Year
- 1999
- Tongue
- English
- Weight
- 486 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0732-8311
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๐ SIMILAR VOLUMES
## Abstract LโGlucose derivatives are prepared by two different routes. The first involves a modification of the previously reported multiโstep approach by __Shiozaki__^8^, starting from a Dโglucuronoโ1,5โlactone derivative, resulting in the isolation of 2,3,4,6โtetraโ__O__โbenzylโLโglucopyranose.
Polyoxamic acid , 2-amino-2-deoxy-L-xylonic acid, is synthetized by thiophenoxide opening of a five-carbon chiral hydroxylated aziridine easily derived from L-arabinose. The formation of the carboxy group resulted lrom a Pummerer reaction. Polyoxins belong to a group of antifungal antibiotics produc