𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A practical synthesis of a key intermediate for the production of β-lactam antibiotics

✍ Scribed by Gianfranco Cainelli; Paola Galletti; Daria Giacomini

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
208 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Diastereoselective synthesis of a key in
Diastereoselective synthesis of a key intermediate for the preparation of tricyclic β-lactam antibiotics
✍ Takaji Matsumoto; Toshiyuki Murayama; Shigeru Mitsuhashi; Takashi Miura 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 236 KB

Asymmetric synthesis of (S)-5 has been accomplished with an excellent enantiomeric excess by hydrogenation of raeemie 5 using ruthenium-BINAP-diamine-KOH system, followed by oxidation. Magnesium enolate of (2S)-2-methoxycyclohexanone [(S)-5] reacts with the 4-aeetoxyazetidinone 4 to give the key int

Synthesis of a potential intermediate to
Synthesis of a potential intermediate to β-lactam antibiotics
✍ Andrew Freer; Karl Overton; Richard Tomanek 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 170 KB

Cycloaddition of nitrone (2) to a-chloroacrylonitrile followed by hydrolysis afforded the isoxazolidinone (I) as a single diastereomer.