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A Practical Synthesis of 4′-Methylbiphenyl-2-carbonitrile as a Key Intermediate of Angiotensin II Antagonists

✍ Scribed by Noda, Yumiki; Akiba, Yoshikazu; Kashima, Mikito


Book ID
121730046
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
273 KB
Volume
26
Category
Article
ISSN
0039-7911

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A Practical Synthesis of 4'-Methylbiphenyl-2-carbonitrile as a Key Intermediate of Angiotensin II Antagonists. -A novel and practical synthesis of the title carbonitrile (VI), which is applicable to industrial scale production, is described. The key feature of the short sequence is the Pdcatalyzed

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