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A possible association between missense polymorphism of the breakpoint cluster region gene and lithium prophylaxis in bipolar disorder

✍ Scribed by Takuya Masui; Ryota Hashimoto; Ichiro Kusumi; Katsuji Suzuki; Teruaki Tanaka; Shin Nakagawa; Tatsuyo Suzuki; Nakao Iwata; Norio Ozaki; Tadafumi Kato; Masatoshi Takeda; Hiroshi Kunugi; Tsukasa Koyama

Book ID
116841128
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
144 KB
Volume
32
Category
Article
ISSN
0278-5846

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## Abstract Recent studies have indicated that the brain‐derived neurotrophic factor (__BDNF__) gene is involved in the etiology of bipolar disorder (BPD). Two family‐based association studies showed that the Val allele of the functional polymorphism Val66Met in the __BDNF__ gene is associated with