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A pilot study of docetaxel-carboplatin versus paclitaxel-carboplatin in Japanese patients with epithelial ovarian cancer

โœ Scribed by Taisuke Mori; Kenichi Hosokawa; Yoshiyuki Kinoshita; Ai Watanabe; Takeshi Yamaguchi; Haruo Kuroboshi; Yoshiko Kato; Jinsuke Yasuda; Hiroyuki Fujita; Yoshinori Nakata; Hideo Honjo

Publisher
Springer
Year
2007
Tongue
English
Weight
271 KB
Volume
12
Category
Article
ISSN
1341-9625

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## Abstract ## BACKGROUND: Aberrant DNA methylation is a hallmark of cancer, and DNA methyltransferase inhibitors have demonstrated clinical efficacy in hematologic malignancies. On the basis of preclinical studies indicating that hypomethylating agents can reverse platinum resistance in ovarian c