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A Physiologically Based Pharmacokinetic Model for Methyl Mercury in the Pregnant Rat and Fetus

✍ Scribed by D.G. Gray


Book ID
112265868
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
903 KB
Volume
132
Category
Article
ISSN
0041-008X

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Disposition of p-phenylbenzoic acid (PPBA) in the pregnant Wistar rat (for both mother and fetuses) was predicted by using a physiologically based pharmacokinetic model. This model was constructed from ten organs for the mother and eight organs for fetuses, with fetal blood flow based on anatomical