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A Phase II trial of weekly infusional 5-fluorouracil in combination with lowdose leucovorin in patients with advanced colorectal cancer

✍ Scribed by Naomi B. Haas; Russell J. Schilder; Sherry Nash; Louis M. Weiner; Robert C. Catalano; Robert F. Ozols; Peter J. O'Dwyer

Publisher
Springer US
Year
1995
Tongue
English
Weight
444 KB
Volume
13
Category
Article
ISSN
0167-6997

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✍ Enrique Aranda; AndrΓ©s Cervantes; Javier Dorta; Esperanza Blanco; Carlos FernΓ‘nd πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 419 KB πŸ‘ 2 views

Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer