A phase II study of sunitinib in patients with recurrent and/or metastatic non-nasopharyngeal head and neck cancer
β Scribed by George Fountzilas; Anna Fragkoulidi; Anna Kalogera-Fountzila; Martha Nikolaidou; Mattheos Bobos; Julien Calderaro; Felipe Andreiuolo; Marios Marselos
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 639 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0344-5704
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π SIMILAR VOLUMES
Thirty patients with recurrent and/or metastatic head and neck cancer were treated with sequentially administered methotrexate (MTX) and piritrexim (PTX). The treatment schedule consisted of intravenous (IV) MTX (50 mg/m') administered on day 1 and oral PTX (75 mg/mz) administered twice daily on day
## Abstract ## Background. The aims of this study were to determine the recommended dose (RD) in combination chemotherapy of Sβ1 and carboplatin in recurrent and/or metastatic head and neck cancer (phase I) and to examine response rate and toxicities at RD (phase II). ## Methods. Sβ1 was given o