Phase II study of rubitecan in recurrent or metastatic head and neck cancer
✍ Scribed by Francesco Caponigro; Giacomo Cartenì; Jean Pierre Droz; Amalia Milano; Wayne B. Davis; Patricia Pollard
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 236 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0344-5704
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📜 SIMILAR VOLUMES
Thirty patients with recurrent and/or metastatic head and neck cancer were treated with sequentially administered methotrexate (MTX) and piritrexim (PTX). The treatment schedule consisted of intravenous (IV) MTX (50 mg/m') administered on day 1 and oral PTX (75 mg/mz) administered twice daily on day
## Abstract ## Background. The aims of this study were to determine the recommended dose (RD) in combination chemotherapy of S‐1 and carboplatin in recurrent and/or metastatic head and neck cancer (phase I) and to examine response rate and toxicities at RD (phase II). ## Methods. S‐1 was given o