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A phase I dose-finding study of a combination of pegylated liposomal doxorubicin (Doxil), carboplatin and paclitaxel in ovarian cancer

✍ Scribed by Gibbs, D D; Pyle, L; Allen, M; Vaughan, M; Webb, A; Johnston, S R D; Gore, M E


Book ID
109997222
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
90 KB
Volume
86
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and docetaxel have single‐agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with ad