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A phase 1/2 study of orally administered synthetic hypericin for treatment of recurrent malignant gliomas

✍ Scribed by William T. Couldwell; Amy A. Surnock; Alfonso J. Tobia; Bernard E. Cabana; Charles B. Stillerman; Peter A. Forsyth; Alan J. Appley; Alexander M. Spence; David R. Hinton; Thomas C. Chen

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
838 KB
Volume
117
Category
Article
ISSN
0008-543X

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## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly