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A Peptide Carrier with a Built-In Vaccine Adjuvant: Construction of Immunogenic Conjugates

โœ Scribed by Krikorian, Dimitrios; Panou-Pomonis, Eugenia; Voitharou, Chryssa; Sakarellos, Constantinos; Sakarellos-Daitsiotis, Maria

Book ID
126889546
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
273 KB
Volume
16
Category
Article
ISSN
1043-1802

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Synthetic lipopeptides are showing promise as vaccine candidates, but until now it has been very difficult to prepare them in homogeneous form. We describe the synthesis and characterization of a new water-soluble, four-branched template with a built-in lipophilic adjuvant (Pam3Cys). Through the use