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A One-Pot Synthesis of trans - N -Alkylaziridine-2-carboxylates from Amino Alcohol Esters

✍ Scribed by Kaabi, Amani; Elemine, Brahim Ould; Besbes, Rafâa

Book ID
121512198
Publisher
Taylor and Francis Group
Year
2011
Tongue
English
Weight
221 KB
Volume
41
Category
Article
ISSN
0039-7911

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## Abstract A short synthesis of __N__,1,2‐trisubstituted vicinal amino alcohols by 1,2‐addition of deprotonated __N__‐monosubstituted α‐amino nitriles to aldehydes and subsequent one‐pot reduction of the intermediates with borane–THF is described. This procedure leads to the predominant formation