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CeO2-catalysed one-pot selective synthesis of esters from nitriles and alcohols

✍ Scribed by Tamura, Masazumi; Tonomura, Takuya; Shimizu, Ken-ichi; Satsuma, Atsushi


Book ID
119969951
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
303 KB
Volume
14
Category
Article
ISSN
1463-9262

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✍ Coralie Kison; Till Opatz πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 159 KB πŸ‘ 1 views

## Abstract A short synthesis of __N__,1,2‐trisubstituted vicinal amino alcohols by 1,2‐addition of deprotonated __N__‐monosubstituted α‐amino nitriles to aldehydes and subsequent one‐pot reduction of the intermediates with borane–THF is described. This procedure leads to the predominant formation