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A One-Pot Process for the Enantioselective Synthesis of Amines via Reductive Amination under Transfer Hydrogenation Conditions

✍ Scribed by Williams, Glynn D.; Pike, Richard A.; Wade, Charles E.; Wills, Martin


Book ID
119998014
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
74 KB
Volume
5
Category
Article
ISSN
1523-7060

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Selective one-pot synthesis of secondary
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Secondary and tertiary amines are selectively prepared in high yields by a one-pot reduction / multiple alkylation procedure from aromatic nitro compounds with styrenes, cyclic olefins or heterofunctionalised olefins, carbon monoxide and hydrogen in the presence of [Rh(cod)CIL as catalyst.