A novel t(5;11)(q31;p15) involving the NUP98 gene on 11p15 is associated with a loss of the EGR1 gene on 5q31 in a patient with acute myeloid leukemia
β Scribed by Yong Wang; Yongquan Xue; Suning Chen; Yafang Wu; Jinlan Pan; Jun Zhang; Juan Shen
- Book ID
- 113513708
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 410 KB
- Volume
- 199
- Category
- Article
- ISSN
- 0165-4608
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The nucleoporin gene NUP98 has been reported to be fused to 9 partner genes in hematologic malignancies with 11p15 translocations. The NUP98-HOXA9 fusion gene has been identified in acute myeloid leukemia (AML) and chronic myelogenous leukemia with t(7;11)(p15;p15). We report here a novel NUP98 part