The nucleoporin gene NUP98 has been reported to be fused to 9 partner genes in hematologic malignancies with 11p15 translocations. The NUP98-HOXA9 fusion gene has been identified in acute myeloid leukemia (AML) and chronic myelogenous leukemia with t(7;11)(p15;p15). We report here a novel NUP98 part
Involvement of theNUP98Gene in a Chromosomal Translocation t(11;20)(p15;q11.2) in a Patient With Acute Monocytic Leukemia (FAB-M5b)
โ Scribed by Naoki Kakazu; Isaku Shinzato; Yasuhito Arai; Saori Gotoh; Akiko Matsushita; Takayuki Ishikawa; Kenichi Nagai; Takayuki Takahashi; Tatsuji Ohno; Takayuki Tsuchiya; Misao Ohki; Tatsuo Abe
- Publisher
- Carden Jennings Publishing
- Year
- 2001
- Tongue
- English
- Weight
- 326 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0925-5710
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Chronic myeloid leukemia (CML) is characterized by the presence of a t(9;22)(q34;q11.2), which leads to the wellโknown BCRโABL1 fusion protein. We describe a patient who was diagnosed clinically with a typical CML but on cytogenetic analysis was found to have a t(9;22)(p24;q11.2). Chrom
## Abstract Greig cephalopolysyndactyly (GCPS; OMIM 175700) is an autosomal dominant condition caused by mutations of the gene __GLI3__, located on 7p13. To date, several cases of deletions and/or translocations involving this locus have been reported in patients with GCPS. __GLI3__ is a transcript