𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel synthesis of β-lactones

✍ Scribed by S.H. Schroeter

Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
141 KB
Volume
10
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A diastereospecific, non-racemic synthes
A diastereospecific, non-racemic synthesis of a novel β-hydroxy-δ-lactone HMG-CoA reductase inhibitor
✍ M. Sletzinger; T.R. Verhoeven; R.P. Volante; J.M. McNamara; E.G. Corley; T.M.H. 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 232 KB

The coupling of acyl anion equivalent 12b with chiral synthon 14, derived from isoascorbic acid, and a highly stereospecific reduction of the resulting e-Tydroxy ketone 3 highlight an efficient synthesis of 8-hydroxy-&lactone 2. -

Synthesis of (−)-noranisatin, an oxidati
Synthesis of (−)-noranisatin, an oxidation product of a neurotoxic sesquiterpenoid anisatin having a novel spiro β-lactone
✍ Haruki Niwa; Shigeki Ito; Takashi Hasegawa; Kazumasa Wakamatsu; Tatsuya Mori; Ki 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 128 KB

The synthesis of (-)-noranisatin (2), an oxidation product of anisatin (1) possessing a novel Spiro P-lactone,was achieved starting from trio1 5 prepared from (R)-(+)-pulegone (3). Anisatin (1) is a neurotoxic sesquiterpenoid isolated from the seeds of Japanese star anise (Illicium anisurum L., shi

Synthesis of δ-lactone, oxetane and azet
Synthesis of δ-lactone, oxetane and azetidinone analogs from the naturally occurring β-lactone L-659,699. The preparation of a novel HMG CoA synthase inhibitor.
✍ Kathryn L. Thompson; Michael N. Chang; Yuan-Ching P. Chiang; Shu Shu Yang; John 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 246 KB

A series of S-lactone (1 and Z), oxetane (3) and azetidinone (4 and 5) analogs were prepared from the HMG CoA synthase inhibitor L-659.699 ((E,E)-ll-[3'R-~ydymethyl)-4'-oxo-2'R-oxetanyl]-3,5,7Rtrimethyl-2,4-undecadienoic acid1v2), which maintained the truns relationship of the ring side chains. The