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A novel synthesis of spirocyclic pyrrolidin-2-ones

✍ Scribed by John M.D Storey

Book ID
104210977
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
70 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

A short synthesis of a series of spirocyclic pyrrolidin-2-ones is presented which proceeds via initial [1,5]-radical translocation followed by cyclisation.

📜 SIMILAR VOLUMES

Synthesis of novel pyrrolidin-2-ones: γ-
Synthesis of novel pyrrolidin-2-ones: γ-aminobutyric acid cyclic analogues
✍ S. Al Akoum Ebrik; B. Rigo; C. Vaccher; M-P. Vaccher; N. Flouquet; M. Debaert; P 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 355 KB

## Abstract Some new __N__‐substituted pyrrolidin‐2‐ones, cyclic analogues of baclofen and of 3‐(5‐methoxybenzo‐[__b__]furan‐2‐yl)‐γ‐aminobutyric acid, have been prepared and characterized, starting from 4‐(4‐chlorophenyl)‐pyrrolidin‐2‐one and 4‐(5‐methoxybenzo[__b__]furan‐2‐yl)pyrrolidin‐2‐one.