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A Novel Solid-Phase Synthesis of Quinolines

✍ Scribed by Tang, E; Mao, Deshou; Li, Wen; Gao, Zhangyong; Yao, Pengfei

Book ID
111676964
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2012
Tongue
English
Weight
717 KB
Volume
85
Category
Article
ISSN
0385-5414

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## Abstract A synthesis of quinoline derivatives is described __via__ reaction between ethyl bromopyruvate (=ethyl 3‐bromo‐2‐oxopropanoate), acetylenedicarboxylate, and isatin (=1__H__‐indole‐2,3‐dione) in the presence of NaH as a base. Also, these reactions were performed without ethyl bromopyruva