A novel route to aldehydic enol ethers and enamines
โ Scribed by J.C. Gilbert; U. Weerasooriya
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 239 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Base-promoted reaction of dimethyl diazomethylphosphonate (1) with dialkyl and cyclic ketones in the presence of alcohols and of amines affords aldehydic enol ethers and enamines, respectively.
๐ SIMILAR VOLUMES
Silyl enol ethers are currently much interested in respect to the reaction of enolate anion, and many reports have been made on the formation and spectra of these compounds. 1 Little has been known, however, about the reactivity on the @-carbon of these compounds except trimethylsilylacetals. 2 We
Methyl 2-siloxycyclopropanecarboxylates rearrange smocthly and quantitatively to the corresponding silyl enol ethers (2) by addition of a catalytical amount of lodo trimethylsilane. Scope and limitation of this novel process as well as the synthesis of the electron rich diene (lea\_) are described.