A Novel PNA-Monomer for Recognition of Thymine in Triple-Helix Structures
β Scribed by Anne Goldbech Olesen; Otto Dahl; Peter E. Nielsen
- Book ID
- 101958203
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 57 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
We have synthesized a new class of modified nucleoside, X, that could recognize adenine-thymine base pairs. They were designed to form the triple helix of A-ToX motif, where X forms hydrogen bonds to the N7 and NH2 of the far-side adenine in the major groove. Compounds 1 and 2 are a new type of trip
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