A novel one pot synthesis of 2-dimethylaminoquinoline derivatives from arylazido ketones by cyclization under vilsmeier condition
โ Scribed by Ramiya R. Amaresh; Paramasivan T. Perumal
- Book ID
- 108386751
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 186 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Studies have been carried out on a new novel method for the synthesis of 2-(N,Ndisubstituted)aminoquinoline via intramolecular electrophilic substitution of methyleniminium salts by azide. Treatment of l-(2-azidophenyl)ethanone with Vilsmeier reagent (DMF/POC13) gave 4-chloro-2dimethylamino-3-quinol
A Novel One-Pot Synthesis of 2-Aminoquinolines from Arylazidoketones by Cyclization under Vilsmeier Conditions. -The reaction of Vilsmeier reagent with 2-azidophenyl ketones is investigated. 1-(2-Azidophenyl)ethanone (I) yields a mixture of the aminoquinolines (III) and (IV). Unexpectedly, the anal