A Novel One-Pot Reformatsky Type Reaction via Bismuth Salt in Aqueous Media. -BiCl3-Al is found to be an effective reagent for the Reformatsky-type reaction of Ξ±-bromoketones (I) and various aldehydes to yield the corresponding Ξ²-hydroxy compounds. Similar treatment of 2-bromocyclohexanone (IV) giv
A novel one-pot reformatsky type reaction via bismuth salt in aqueous media
β Scribed by Zhen Shen; Jinqi Zhang; Huixian Zou; Minmin Yang
- Book ID
- 104256822
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 125 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Ill tile prescnce of bismuth( 111 )chloride-metallic aluminum, ~-halo carbonyl compounds react ~ilh aldehydes in water under mild conditions to give I~-hydrox'y carbonyl compounds with stereoselcctivity in good yields.
π SIMILAR VOLUMES
The first direct organocatalytic asymmetric Mannich-type reactions in aqueous media are demonstrated herein. L-Proline-catalyzed reactions in aqueous media to provide b-formyl substituted a-amino acid derivatives with excellent diastereoselectivities (dr up to 19:1, syn/anti ) and high enantioselect
## Abstract magnified image A short and facile synthesis of pyrido[2,3β__d__]pyrimidine derivatives was accomplished in good yields __via__ the threeβcomponent reaction of aldehydes, alkyl nitriles and aminopyrimidines in water in the presence of triethylbenzylammonium chloride (TEBAC). The struct