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A novel one-pot annelation, decarboxylation reaction: synthesis of (±)-trans-benzohydrindane

✍ Scribed by T Ravindranathan; Subhash P Chavan; Sachindra S Patil; Ganesh Pai


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
96 KB
Volume
43
Category
Article
ISSN
0040-4039

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## Abstract A synthesis of quinoline derivatives is described __via__ reaction between ethyl bromopyruvate (=ethyl 3‐bromo‐2‐oxopropanoate), acetylenedicarboxylate, and isatin (=1__H__‐indole‐2,3‐dione) in the presence of NaH as a base. Also, these reactions were performed without ethyl bromopyruva