A novel one-pot, three-component reaction for the synthesis of isocoumarin-condensed pyrazoles
✍ Scribed by Sevil Ozcan; Cagatay Dengiz; Murat K. Deliömeroglu; Ertan Sahin; Metin Balci
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 512 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
An efficient and general one-pot procedure for the synthesis of pyrazoles from acid chlorides, terminal alkynes and hydrazines was described via a coupling and cyclocondensation sequence. Acid chlorides coupled with terminal alkynes to give a,b-unsaturated ynones, and in situ converted into pyrazole
We have discovered a new reaction whereby 2-substituted azoles are formed in the reaction of an azolium ylide with reactive carbonyl compounds. These products contain a leaving group in the a-position, which on solvolysis in the presence of nucleophiles yield azoles with a variety of a-substituents.
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