𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel on-resin synthesis of C-terminally amidated peptides

✍ Scribed by Kalle Kaljuste; James P. Tam


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
226 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Internal resin capture β€” A self purifica
✍ Michael Davies; Mark Bradley πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 698 KB

A synthetic strategy which allows for the general modification of peptides at the C-terminus has long been the goal of the synthetic chemist. We report here the full synthetic details of our inversion and modification methodology demonstrating the method with the synthesis of peptide amides, alcohol

Removal of C-terminal peptide amides fro
✍ Daniel H. Rich; S.K. Gurwara πŸ“‚ Article πŸ“… 1975 πŸ› Elsevier Science 🌐 French βš– 194 KB

The C-terminal amide group is present in several biologically active peptides including deamino-oxytocin, 1 LH\_m;\*'3 and secretin. 4 These peptides have been synthesized by solid phase methods' in which the C-terminal amide of the protected peptide was removed from the resin by amminolysis or tran

Benzhydrylamine linker grafting: a strat
✍ Dianne Alewood; Gene Hopping; Andreas Brust; Robert C. Reid; Paul F. Alewood πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 219 KB

## Abstract The standard __p__‐MBHA resin used during Boc‐chemistry synthesis of peptides carrying __C__‐terminal carboxamides is compromised by batch‐to‐batch variations in its performance. This can cause artificially β€˜difficult’ couplings during peptide chain assembly, which may ultimately lead t

A comparison of acid labile linkage agen
✍ Michael S. Bernatowicz; Scott B. Daniels; Hubert KΓΆster πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 261 KB

linkage agents useful for the so1id phase peptic synthesis of C-terminal d&s were evaluated for their relative lability toward trifluoroacetic acid. The twomst reactive linkage agents StUdied\*re cved in the synthesis of two different peptide amides by the Na-9-fluoreny~~Yloxycarbony1 protecting gro