A novel method for the synthesis of purine α-ribonucleosides
✍ Scribed by Yoshiyasu Furukawa; Kin-ichi Imai; Mikio Honjo
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- French
- Weight
- 202 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0040-4039
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We report a new method for protecting nucleosides for hydrogen phosphonate RNA synthesis that gives very high yields for the purines. This method is based on our finding that, for adenosine and guanosine, silylation of a mixture of 2' and 3' H-phosphonates in the presence of DBU is highly selective
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