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A novel kainate receptor ligand [3H]-(2S,4R)-4-methylglutamate: Pharmacological characterization in rabbit brain membranes

✍ Scribed by N.J. Toms; M.E. Reid; W. Phillips; M.C. Kemp; P.J. Roberts


Book ID
117187997
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
647 KB
Volume
36
Category
Article
ISSN
0028-3908

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## Abstract Transporters for L‐glutamate (excitatory amino acid transporters; EAATs), localized to astrocytes, are involved intimately in intermediary metabolism within the brain. Because (2__S__,4__R__)‐4‐methylglutamate (4MG) has affinity for glial EAATs, we employed [^3^H]4MG to define the chara

Pharmacological characterisation and inh