✦ LIBER ✦

Pharmacological characterisation and inhibitory effects of (2R,3R,4S,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol, a novel ligand that demonstrates both adenosine A2A receptor agonist and adenosine A3 receptor antagonist activity

✍ Scribed by Nicola Bevan; Peter R. Butchers; Rick Cousins; Jill Coates; Emma V. Edgar; Val Morrison; Michael J. Sheehan; Julian Reeves; David J. Wilson

Book ID: 113586778
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 241 KB
Volume: 564
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2007.01.094

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-c

(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a Selective and Orally Active Neuropeptide Y Y5 Receptor Antagonist

✍ Sato, Nagaaki; Jitsuoka, Makoto; Shibata, Takunobu; Hirohashi, Tomoko; Nonoshita 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 107 KB

A Study on the Allylic Substitution of (

A Study on the Allylic Substitution of (1R,5R,8R)- and (1R,5R,8S)-8-Hydroxy-2-oxabicyclo[3.3.0]oct-6-en-3-one Derivatives − Preparation of (1S,2R,3R)-9-[2-Hydroxy-3-(2-hydroxyethyl)cyclopent-4-en-1-yl]-9H-adenine

✍ Steen K. Johansen; Inge Lundt 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 338 KB 👁 2 views

Discovery of ( R )-9-Ethyl-1,3,4,10b-tet

Discovery of ( R )-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1- a ]isoindol- 6(2 H )-one, a Selective, Orally Active Agonist of the 5-HT 2C Receptor

✍ Wacker, Dean A.; Varnes, Jeffrey G.; Malmstrom, Sarah E.; Cao, Xueying; Hung, Ch 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 191 KB

Synthesis and Pharmacological Characteri

Synthesis and Pharmacological Characterization of 3-[2-((3a R ,9b R )- cis -6-Methoxy- 2,3,3a,4,5,9b-hexahydro-1 H - benz[ e ]isoindol-2-yl)ethyl]pyrido[3‘,4‘:4,5]thieno[3,2- d ]pyrimidine- 2,4(1 H ,3 H )-dione (A-131701): A Uroselective α 1A Adrenoceptor Antagonist for the Symptomatic Treatment of Benign Prostatic Hyperplasia 1

✍ Meyer, Michael D.; Altenbach, Robert J.; Basha, Fatima Z.; Carroll, William A.; 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 134 KB

ChemInform Abstract: Synthesis and Biolo

ChemInform Abstract: Synthesis and Biological Evaluation of Novel 9-Heteroaryl Substituted 7-Chloro-4,5-dihydro-4-oxo-1,2,4-triazolo [1,5-a]quinoxaline-2-carboxylates (TQX) as (R,S)-2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid (AMPA) Receptor Antagonists.

✍ Daniela Catarzi; Vittoria Colotta; Flavia Varano; Guido Filacchioni; Paola Gratt 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 45 KB 👁 1 views

Synthesis of Ethyl (1 S ,2 R ,3 S ,4 S,

Synthesis of Ethyl (1 S ,2 R ,3 S ,4 S, 5 S )-2,3- O -(Isopropylidene)-4-Hydroxy-Bicyclo[3.1.0]Hexane-Carboxylate from L-Ribose: A Versatile Chiral Synthon for Preparation of Adenosine and P2 Receptor Ligands

✍ Joshi, Bhalchandra V.; Melman, Artem; Mackman, Richard L.; Jacobson, Kenneth A. 📂 Article 📅 2008 🏛 Taylor and Francis Group 🌐 English ⚖ 308 KB