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A novel improved synthesis of 3-aminopyrazine-2-carboxylic acid

✍ Scribed by Paul R. Buckland

Book ID
112125962
Publisher
Journal of Heterocyclic Chemistry
Year
1980
Tongue
English
Weight
107 KB
Volume
17
Category
Article
ISSN
0022-152X

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## Abstract The 3‐chloro and 3‐bromo‐2‐phenylquinoline‐4‐carboxylic acids were obtained in good yields through a novel procedure, entailing the synthesis of the 3‐amino intermediate and the subsequent replacement of the amino group with chlorine or bromine, according to the Sandmeyer reaction.