An efficient large-scale synthesis of 1H
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Richard V. Coelho Jr.; Klaas Schildknegt
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Article
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2007
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John Wiley and Sons
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French
β 89 KB
## Abstract An efficient largeβscale carbonβ14 synthesis of 1__H__βindazoleβ[3β^14^C]carboxylic acid starting from [^14^C]potassium cyanide is reported. Key transformations encountered during the synthesis include aromatic nucleophilic substitution of 2βnitrofluorobenzene by ethyl [^14^C]cyanoaceta