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A novel synthesis of 3-halo-2-phenylquinoline-4-carboxylic acids

✍ Scribed by Luca F. Raveglia; Giuseppe A. M. Giardina; Mario Grugni; Roberto Rigolio; Carlo Farina

Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
260 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

The 3‐chloro and 3‐bromo‐2‐phenylquinoline‐4‐carboxylic acids were obtained in good yields through a novel procedure, entailing the synthesis of the 3‐amino intermediate and the subsequent replacement of the amino group with chlorine or bromine, according to the Sandmeyer reaction.

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