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A Novel Highly Stereoselective Synthesis of 2,3-Disubstituted 3H-Quinazoline-4-one Derivatives

โœ Scribed by Zhichkin, Paul; Kesicki, Edward; Treiberg, Jennifer; Bourdon, Lisa; Ronsheim, Matthew; Ooi, Hua Chee; White, Stephen; Judkins, Angela; Fairfax, David

Book ID
115468557
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
82 KB
Volume
9
Category
Article
ISSN
1523-7060

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A Novel Highly Stereoselective Synthesis
A Novel Highly Stereoselective Synthesis of 2,3-Disubstituted 3H-Quinazoline-4-one Derivatives.
โœ Paul Zhichkin; Edward Kesicki; Jennifer Treiberg; Lisa Bourdon; Matthew Ronsheim ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons โš– 39 KB ๐Ÿ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

ChemInform Abstract: Stereoselective Syn
ChemInform Abstract: Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one.
โœ M. SZABO; J. KOEKOESI; A. KOVACS; Z. BOECSKEI; I. HERMECZ ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB ๐Ÿ‘ 1 views

Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one. -Thermal acylation of the quinazolinone (III) with ethyl acetoacetate and subsequent thermal cyclization of the intermediate acetoacetamide results in selective formation of the title compound (V),