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ChemInform Abstract: Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one.

โœ Scribed by M. SZABO; J. KOEKOESI; A. KOVACS; Z. BOECSKEI; I. HERMECZ

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one.

-Thermal acylation of the quinazolinone (III) with ethyl acetoacetate and subsequent thermal cyclization of the intermediate acetoacetamide results in selective formation of the title compound (V), which may be of interest as pharmaceutical agent. -(SZABO,

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