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ChemInform Abstract: Synthesis and Pharmacological Activities of Novel 3-(Isoxazol-3-yl)-quinazolin-4(3H)-one Derivatives.

โœ Scribed by Giuseppe Daidone; Demetrio Raffa; Benedetta Maggio; Fabiana Plescia; Vincenza Maria Catena Cutuli; Nunzio Guido Mangano; Antonina Caruso

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Synthesis and Pharmacological Activities of Novel 3-(Isoxazol-3-yl)quinazolin-4(3H)-one Derivatives.

-Twelve title derivatives such as (I) are synthesized by a previously described method and tested for their analgesic and antiinflammatory activities as well as for their acute toxicity and ulcerogenic effect. Compounds (Ia) and (Ie) are endowed with appreciable analgesic and antiinflammatory activities and with low systemic toxicity and very modest ulcerogenic effects. -(DAIDONE, GIUSEPPE; RAFFA,

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